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Biopolymers Stimulate Nerve Regeneration

In the journal Advanced Materials, Yadong Wang, assistant professor in the Coulter Department of Biomedical Engineering at Georgia Tech and Emory University, developed a treatment for recovering human nerve function.

The technique would use a biodegradable polymer containing a chemical group that mimics the neurotransmitter acetylcholine, because he and the researchers thought that regeneration in the central nervous system requires neural activity, not just neuronal growth factors alone. A neurotransmitter might send the necessary signal to relay, amplify and modulate signals between a neuron and another cell.

Hopefully, it can spur the growth of neurites, which are projections that form the connections among neurons and between neurons and other cells.

The study shows that integrating neurotransmitters into biodegradable polymers results in a biomaterial that successfully promotes neurite growth, which is necessary for victims of central nervous system injury, stroke or certain neurodegenerative diseases to recover sensory, motor, cognitive or autonomic functions.

The research was supported by Georgia Tech, the National Science Foundation and the National Institute of Biomedical Imaging and Bioengineering (NIBIB).

Adapted from : Science Daily

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