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The Combination of Cell Biology and Endocrinology to Eliminate Insulin Implants

Yessi Pratiwi — November 2, 2007 / 7:31 pm

More than 16 million Americans have diabetes, the sixth leading cause of death by disease in the United States. Nowadays, there is a new option to diabetes patients who cannot live without insulin injections. The need of insulin will be covered with the insulin produced from a transplant of islet cells. This is a kind of a cultured human beta cells that can grow indefinitely.

Dr. Paul Gores, director of pancreas and islet transplantation at Carolinas Medical Center in Charlotte, N.C., says, “An islet cell transplant is a means of reversing diabetes in a patient who has lost their beta cells, which are the important cells within the little clusters of cells we call islets, which reside inside the pancreas, which produce insulin.”

Beta cells are found exclusively in the pancreas, secreting insulin in response to glucose stimulation. When these cells are defective or when the body fails to utilize insulin properly, the result is diabetes, characterized by high blood sugar levels.

Transplant surgeons go through a painstaking 14-hour process to isolate and purify the islet cells from a donated pancreas. Those cells will produce insulin.

Well, no guarantee the success will last, but this is a very good choice that offer a much needed source of insulin for diabetic sufferer.

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