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Cancer Molecular Therapy With Nanoparticles

Yessi Pratiwi — October 9, 2007 / 3:06 pm

For you who have been suffered by cancer for such a long time, this therapy may become a new hope. Researchers at Rice University under Prof. Jennifer West, have demonstrated the use of 120 nm diameter nanoshells coated with gold to kill cancer tumors in mice. This nanoshells is targeted to bond to cancerous cells by conjugating antibodies or peptides to the nanoshell surface.

Nanoparticles of cadmium selenide (quantum dots) glow when exposed to ultraviolet light. When injected, they seep into cancer tumors. The surgeon will see the glowing tumor, and use it as a guide for more accurate tumor removal. cancer-molecular-imagingtherapy.JPG

By irradiating the area of the tumor with an infrared laser, which passes through flesh without heating it, the gold is heated sufficiently to cause death to the cancer cells.

James Baker from University of Michigan believes he has discovered a highly efficient and successful way of delivering cancer-treatment drugs that is less harmful to the surrounding body. He developed a nanotechnology that can locate and then eliminate cancerous cells, and looks at a molecule called a dendrimer. He discover that cancer cells have more vitamin receptors than normal cells, so Baker’s vitamin-laden dendrimer will be absorbed by the cancer cell. Baker places anti-cancer drugs that will be absorbed with the dendrimer into the cancer cell, thereby delivering the cancer drug to the cancer cell and nowhere else.

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