You're here: My Health Blogging » General Health » Article: Be Careful, Smokers!
Yessi Pratiwi — July 7, 2007 / 8:18 pm
Smoker’s attention, please! A research shows that nicotine changes your brain and your body function. Need an explanation? OK, then. You get it, right here.
Our brain have millions of neurons, the cells that transfer and integrate information. Each neuron has thousands of inputs from other neurons throughout the brain. While signals are conducted through individual neurons as electric current, communication between neurons is mediated by chemical messengers, called neurotransmitters. Each neurotransmitter has its own specific family of receptors. Nicotine works by docking to a subset of receptors that bind the neurotransmitter acetylcholine.
While neurons typically release small amounts of acetylcholine in a regulated manner, nicotine activates cholinergic neurons (which mainly use acetylcholine to communicate to other neurons) in many different regions throughout your brain simultaneously. Nicotine also increases the level of other neurotransmitters and chemicals that modulate how your brain works. For example, your brain makes more endorphins in response to nicotine. Endorphins are small proteins that are often called the body’s natural pain killer. It turns out that the chemical structure of endorphins is very similar to that of heavy-duty synthetic painkillers like morphine. Endorphins can lead to feelings of euphoria also.
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